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HCG:
Substance: Human Chorionic Gonadotropin
Information
HCG "Human Chorionic Gonadotropin" drug is not a steroid but it is widely used in athletics today. HCG is a natural protein hormone secreted by the human placenta and purified form the urine of pregnant women. This hormone is not a natural male hormone but mimics the natural hormone LH (Luetinising Hormone) almost identically. This LH stimulates the production of testosterone by the testis in males. Thus HCG sends the same message and results in increased testosterone production by the testis due to HCG’s effect on the leydig cells of the testis. Normally this HCG is used to treat women with certain ovarian disorders and it is used to stimulate the testis of men who may be hypogonadal. Athletes use HCG to increase the body’s own natural production of testosterone which is often depressed by long term steroid use. Also when steroids are used in high dosages they can cause false signals to the hypothalamus that results in a depressed signal to the testicles. Over a period of weeks of this depressed signal the testicles ability to respond to any signal from the pituitary becomes very weak, which results in testicular atrophy. To avoid this athletes will use HCG to keep an artificial signal going to the testis and preventing testicular atrophy.
The side effects from HCG use include gynecomastia, water retention, and an increase in sex drive, mood alterations, headaches, and high blood pressure. HCG raises androgen levels in males by up to 400% but it also raises estrogen levels dramatically as well. This is why it can cause a real case of gynecomastia if dosages get too elevated for that person. Another side effect seen from HCG use is morning sickness (nausea and vomiting).
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