What are the different types of anabolic steroids?
Testosterone, like many other hormones, is produced only at certain sites in the body. It does very limited, specific functions and is quickly metabolized. When testosterone was found to build muscle tissue and to cause the development of male secondary sex characteristics, medical researchers tried to use testosterone to treat diseases that caused the loss of muscle mass.(1-3) Unfortunately, testosterone in its natural form has a half life of only about ten minutes in the body.(4) This means that half of the dose of testosterone is metabolized away in as little as ten minutes after it is absorbed. Half of what remains is broken down every ten minutes after that. At the end of an hour, none of the original dose of testosterone can be detected in the body. Injecting natural testosterone into muscle can make it last as long as ten hours, but this is still not nearly long enough to be useful as a medicine.(1) Medicinal chemists began to alter natural testosterone in an attempt to make drugs that would work like testosterone but last long enough in the body to have an effect. After extensive testing, they found that changing the testosterone molecule at one of only a few specific places would give them what they wanted-- anabolic steroid drugs.(5) These variations are known by chemists as "17-alpha-alkylates", "17-beta-esters", and "1-methyl" steroids.(5) All anabolic steroids in use today are variations of one of those three changes to the testosterone molecule. These chemical classes of anabolics are taken by different routes and have different side effects on the body. The 17-alpha-alkylates and 1-methyl compounds are taken by mouth, while 17-beta-esters must be injected to be effective.(1,5) For convenience, they will be classified here as oral or injectable steroids. Oral Steroids: Oral steroids can be detected in the body for several weeks after a person stops taking them.(6) This is enough time to make them useful as medicines, but still a short duration of action compared with the injectable steroids.(7) Athletes usually experiment with oral anabolics at first. They are convenient to store and use, but cause severe side effects to the liver in addition to the side effects caused by all anabolics.(8-10) These side effects are described in detail under the question, "Do anabolic steroids cause liver damage?" An athlete will usually continue to use oral drugs even when he or she begins using injectable steroids. Some use orals to make it easier to escape drug detection tests: Most oral anabolic steroids do not remain in the body as long as injectables. As an event approaches, an athlete may use shorter-duration oral steroids, then stop using four to six weeks before the event so that the urine will be steroid-free for urine testing. Many athletes and trainers also believe that it is necessary to use oral and injectable steroids at the same time, in certain patterns. This topic is covered in detail under the question, "How are anabolics used by athletes?" Injectable Steroids: Injectable anabolics are injected into muscle tissue, not into the veins. They are slowly released from the muscles into the rest of the body, and may be detectable for months after last use.(11) Chemically, the injectable steroids are better tolerated by the body than the oral steroids. Long-term steroid abusers begin to use them for this reason. However, injection of any substance creates its own risks and health problems. Injecting a drug bypasses the body's natural defense mechanisms against poisoning and infection. If a person accidentally swallows too much of a drug, he or she may vomit before enough has been absorbed to cause death. If a person inhales poisonous smoke or fumes, the coughing reflex may prevent poisoning. But if a person injects too much of a drug, there is no easy way to get it back out of the body. When injections are given in a doctor's office or at the hospital, great care is taken to sterilize the skin before the drug is given. Diabetics are taught how to take these same precautions so that when they inject insulin, they do not cause infection. Without such precautions, the needle has the ability to carry dirt and bacteria past the protection of the skin. Hepatitis, abscesses, and other infections often result from lack of good sterile technique.(8,12) There have been two cases of AIDS reported in body builders who shared needles with other body builders.(8,13) Injectable anabolics are considered gateway drugs to injectable drug abuse: A person who becomes accustomed to injecting anabolics will be more likely to experiment with injecting other drugs than a person who has never injected anything. This gateway principle applies to other drugs as well. For example, people who smoke tobacco are more likely to try smoking marijuana or crack than those who do not smoke at all. In our society, people do not enjoy injecting themselves with syringes. Even diabetics learn to do it only with difficulty. A steroid abuser who becomes accustomed to injecting him- or herself with anabolics has a higher risk of injecting cocaine or heroin than an illicit drug user who does not inject. REFERENCES 1. Scott MJ, Scott MJ. HIV infection associated with injections of anabolic steroids. J Am Med Assoc 1989 Jul;262(2):207- 8. by Trent Tschirgi, R. Ph. (c) 1992 University of Maryland Office of Substance Abuse Studies. All Rights Reserved.
Disclaimer: Steroid use is illegal in a vast number of countries around the world. This is not without reason. Steroids should only be used when prescribed by your doctor and under close supervision. Steroid use is not to be taken lightly and we do not in any way endorse or approve of illegal drug use. The information is provided on the same basis as all the other information on this site, as informational/entertainment value.
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