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Substance: 2,4-Dinitrophenol


DNP 2, 4-Dinitrophenol was originally made as a replacement detonating compound in TNT. When used in humans, however, DNP will raise body temperature by interfering with mitochondria oxidative phosphorylation. The way that this is accomplished in the body is that DNP diverts fatty acids away from ATP production and throws them off as heat instead. Aspirin, clenbuterol, and ephedrine all do the same thing but to a much lower extent. This is why you feel your body temperature rising when using these compounds. 

DNP 2, 4-Dinitrophenol was used as a fat loss diet drug in the 1930's. There was a 1% incidence of users developing cataracts though and since DNP was not listed as one of the ingredients in these weight loss dieting drugs, they were pulled from the market. The thing that makes DNP so alluring to most bodybuilders is that it boosts metabolism.

This product is very dangerous to use though. An overdose of only 4 times the recommended one will kill you. As far as this product raising your body temperature, it can raise it indefinitely as well. You can die or suffer brain damage after your body temperature goes over 104 degrees. DNP can raise your temperature much higher than that as well. If brain damage and death are not bad enough side effects to you, you can also suffer irreversible liver damage and/or kidney damage as well without even an overdose while using this product if you stay on it for too long. This makes DNP a very deadly substance to mess with. Probably the most deadly thing a bodybuilder can take.

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